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These findings also support observations made by other authors, who have shown that PEF contributes to the release of autolytic enzymes located in the lysosomes of the cytoplasm ( FIGURE 7 Figure 7 also shows that once the supernatant was removed after 24 h of incubation, enzymatic activity was still observed in the media in which the biomass had been re-suspended

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Macrophage activation is central to PNI pathogenesis, transitioning from a proinflammatory (M1) to an anti-inflammatory (M2) phenotype with distinct functions in inflammation and repair

10.1016/j.phymed.2022.153942 32 GuoM.WangZ.DaiJ.FanH.YuanN.GaoL.et al (2023)